Publications by authors named "L Roten"
Background: Either dual antiplatelet therapy or oral anticoagulation in combination with aspirin represent recommended treatment regimens following left atrial appendage closure (LAAC). As the majority of patients receiving LAAC have high bleeding risk, less aggressive antithrombotic treatments are needed, such as single antiplatelet therapy.
Objectives: To compare both ischemic and bleeding outcomes in patients receiving single (SAPT) or dual antiplatelet therapy (DAPT) after successful LAAC.
Background: Early recurrences of atrial tachyarrhythmias (ERATs) after pulmonary vein isolation (PVI) are common. While many correlate to late recurrences (LRs), some do not. The impact of ERATs timing is difficult to assess with noninvasive Holter monitoring because of undersampling.
View Article and Find Full Text PDFPulsed Field Ablation as First-Line Therapy for Atrial Fibrillation: A Substudy of the EU-PORIA Registry.
Circ Arrhythm Electrophysiol
December 2024
Background: Recent studies have demonstrated the benefit of early ablation in preventing the progression of atrial fibrillation (AF). Clinical practice has reflected this shift in AF management and no longer requires patients to fail antiarrhythmic drugs (AADs) before receiving ablation. However, there is limited evidence on outcomes with pulsed field ablation (PFA) as a first-line therapy.
View Article and Find Full Text PDFArticle Synopsis
- Single-shot devices, like the Arctic Front cryoballoon, are becoming popular for pulmonary vein isolation in atrial fibrillation, with a new option, the FARAPULSE pulsed field ablation device, aiming for better safety and effectiveness.
- The SINGLE SHOT CHAMPION trial involves 210 patients with paroxysmal atrial fibrillation randomly assigned to either the FARAPULSE or the cryoballoon treatment, with thorough monitoring for outcomes.
- The study's primary focus is on the first recurrence of atrial tachyarrhythmias within a year after the procedure, alongside safety measures and quality of life assessments.
Article Synopsis
- - The study compared the effects of dexmedetomidine and propofol on heart function in patients undergoing atrial fibrillation ablation, focusing on how each sedative impacts sinus node function and atrioventricular (AV) conduction.
- - A total of 160 patients were enrolled, with findings indicating that patients given dexmedetomidine experienced slower sinus rates and prolonged AV conduction times compared to those given propofol.
- - Despite these differences, both sedatives did not significantly affect certain aspects of heart conduction, such as infrahissian AV conduction and ventricular repolarization, and arrhythmia occurrence was similar across both groups.