Publications by authors named "L Rizzoli"

Article Synopsis
  • The study investigates the dermatological manifestations of COVID-19 in children, particularly noting the prevalence of chilblain-like lesions among infected and non-infected patients, attributed to a pronounced interferon response in younger individuals.
  • Conducted over six months, the research involved 137 patients aged 1 to 18 from 23 Italian dermatological units, who exhibited a variety of skin lesions primarily on the feet.
  • Results showed diverse skin symptoms, with many experiencing concomitant systemic symptoms, highlighting the complex interplay of dermatological and respiratory issues related to COVID-19 in children.
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Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous syndrome causing hamartomatous growths in multiple organs. Facial angiofibromas occur in up to 80% of patients and can be highly disfiguring. Treatment for these lesions is challenging.

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The outbreak of chilblain-like lesions (CLL) coincidentally to the COVID-19 pandemic is a topic of great concern. SARS-CoV-2 was initially hypothesized as the etiologic agent of CLL, but, since nasopharyngeal swabs seldom resulted positive, dermatologists' attention focused on the search for specific SARS-CoV-2 antibodies. Many papers were published contemporarily on this topic, reporting limited case series.

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