A Case of Sinus of Valsalva Aneurysm Rupture in a Patient with Bicuspid Aortic Valve.

• SOV-A is defined as abnormal dilation of the aortic root. • This is a rare entity, with an incidence between 0.14% and 3.

Cardiac Paraganglioma: Advantages of Cardiovascular Multimodality Imaging.

• Cardiac paragangliomas are infrequent tumors. • The most common location is in the left atrium. • Cardiovascular morbidity and mortality without treatment are high.

Reduction of the ATPase inhibitory factor 1 (IF) leads to visual impairment in vertebrates.

In vertebrates, mitochondria are tightly preserved energy producing organelles, which sustain nervous system development and function. The understanding of proteins that regulate their homoeostasis in complex animals is therefore critical and doing so via means of systemic analysis pivotal to inform pathophysiological conditions associated with mitochondrial deficiency. With the goal to decipher the role of the ATPase inhibitory factor 1 (IF) in brain development, we employed the zebrafish as elected model reporting that the Atpif1a zebrafish mutant, pinotage (pnt ), which lacks one of the two IF paralogous, exhibits visual impairment alongside increased apoptotic bodies and neuroinflammation in both brain and retina.

Heterogeneity of the neuropeptide Y (NPY) contractile and relaxing receptors in horse penile small arteries.

The distribution of neuropeptide Y (NPY)-immunorective nerves and the receptors involved in the effects of NPY upon electrical field stimulation (EFS)- and noradrenaline (NA)-elicited contractions were investigated in horse penile small arteries. NPY-immunoreactive nerves were widely distributed in the erectile tissues with a particularly high density around penile intracavernous small arteries. In small arteries isolated from the proximal part of the corpora cavernosa, NPY (30 nM) produced a variable modest enhancement of the contractions elicited by both EFS and NA.

An in vitro method of studying functional responses of penile resistance arteries under isobaric conditions.

Purpose: We developed an in vitro method that allows us to study the physiopharmacological responses of penile resistance arteries under isobaric conditions.

Materials And Methods: Second to third order penile resistance arteries (internal diameter 170 to 210 microm) were mounted in a pressure myograph and cannulated at each end with small glass cannulas (tip external diameter 150 to 180 microm). Internal diameter was continuously recorded and monitored under an intraluminal pressure of 60 mm Hg.