Publications by authors named "L Riccardi"
Background: Noninvasive tests (NITs) to monitor metabolic dysfunction-associated steatohepatitis (MASH) progression and response to interventions are needed because of the risks of liver biopsy. A monocytes-based diagnostic test using perilipin-2 (PLIN2) and Ras-related protein-14 (RAB14) predict the severity of MASH and fibrosis. Here we compared the performances of PLIN2 and RAB14 with cytokeratin-18 (CK18) assessed by Ella™ or M65 ELISA in predicting MASH and fibrosis resolution following bariatric surgery in a longitudinal and histologically characterized cohort of individuals with obesity.
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- Ustekinumab (UST) has emerged as a new treatment option for Crohn's disease (CD), but there is a need for predictors of its effectiveness, with contrast-enhanced ultrasound (CEUS) being a promising non-invasive method.
- A study was conducted to evaluate the role of multimodal intestinal ultrasound (IUS) in predicting the treatment response to UST in CD patients who had previously undergone anti-TNFα therapy, assessing various parameters over time.
- Results showed that specific ultrasound measurements, particularly changes in bowel wall thickness and IUS score, effectively predicted long-term therapeutic outcomes in CD patients receiving UST, indicating the potential utility of IUS in clinical settings.
Purpose: Heart failure (HF) is a major health problem affecting millions of people worldwide. In the latest years, many efforts have been made to identify predictors of poor prognosis in these patients. The aim of this systematic review and meta-analysis was to enlighten the correlation between liver stiffness (LS), assessed by Shear Wave Elastography techniques, and HF, particularly focusing on the prognostic value of LS on cardiovascular outcomes.
View Article and Find Full Text PDFHepatocellular carcinoma (HCC) is the most frequent primary liver cancer and the sixth most common malignant tumor in the world, with an incidence of 2-8% per year in patients with hepatic cirrhosis or chronic hepatitis. Despite surveillance schedules, it is sometimes diagnosed at an advanced stage, requiring complex therapeutic efforts with both locoregional and systemic treatments. Traditional radiological tools (computed tomography and magnetic resonance) are used for the post-treatment follow-up of HCC.
View Article and Find Full Text PDF: Heart failure (HF) represents a major health burden. Although several treatment regimens are available, their effectiveness is often unsatisfactory. Growing evidence suggests a pivotal role of the gut in HF.
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