Publications by authors named "L Restier"
Objectives: Refeeding syndrome (RS) defines the deleterious clinical and metabolic changes occurring during nutritional support of severely malnourished patients. Pediatric guidelines to prevent and treat RS are scarce and highly variable. This study aimed to evaluate the effectiveness and safety of an enteral refeeding protocol in severely undernourished hospitalized children with anorexia nervosa (AN) or organic diseases (OD).
View Article and Find Full Text PDFBackground: Heterozygous familial hypercholesterolemia (HeFH) predisposes to premature cardiovascular diseases. Since 2015, the European Atherosclerosis Society has advocated initiation of statins at 8-10 years of age and a low-density lipoprotein cholesterol (LDL-C) target of <135 mg/dL. Longitudinal data from large databases on pharmacological management of pediatric HeFH are lacking.
View Article and Find Full Text PDFArticle Synopsis
- Familial hypobetalipoproteinemias (FHBL) are rare genetic disorders linked to lipid malabsorption, specifically abetalipoproteinemia (FHBL-SD1) and chylomicron retention disease (FHBL-SD3), caused by mutations in MTTP and SAR1B genes.* -
- This study aimed to assess the absorption and levels of carotenoids in patients with these conditions, revealing significant deficiencies in carotenoid levels compared to healthy controls; in lab models, carotenoid absorption was notably reduced.* -
- The findings suggest that despite treatment with fat-soluble vitamins, there's a continued loss in visual function, indicating that carotenoid supplementation could be crucial, and further research is
Objectives: To evaluate short- and long-term safety and efficacy of embolization with Onyx for recurrent pulmonary arteriovenous malformations (PAVMs) in hereditary hemorrhagic telangiectasia (HHT).
Methods: In total, 45 consecutive patients (51% women, mean (SD) age 53 (18) years) with HHT referred to a reference center for treatment of recurrent PAVM were retrospectively included from April 2014 to July 2021. Inclusion criteria included evidence of PAVM recurrence on CT or angiography, embolization using Onyx and a minimal 1-year-follow-up CT or angiography.
Background: Undernutrition has been previously identified as a deleterious factor in acute infections. In covid-19 infection, obesity is a risk-factor of severe evolution, but initial undernutrition has not been evaluated yet.
Methods: We retrospectively analyzed correlation between nutritional status at admission and severe outcomes (intensive care unit admission, invasive mechanical ventilation requirement and death) of patients hospitalized for confirmed covid-19 infection.