Publications by authors named "L Reitnauer"
Thoracic Oncology Highlights from the European Society for Medical Oncology Annual Meeting 2024: Targeted Therapies in Non-Small Cell Lung Cancer (NSCLC).
Oncol Res Treat
December 2024
Article Synopsis
- Extracellular vesicles (EVs) are tiny packets that carry important messages and materials between cells, and in cancer, they help tumors grow by creating a good environment for themselves.
- The study looked at how two specific proteins, ROR1 and ROR2, are delivered to breast cancer cells through EVs and how this affects tumor growth.
- The results showed that even without taking in ROR proteins, the cancer cells could still grow and spread more when exposed to ROR-positive EVs, suggesting they play a big role in making cancer worse.
Background: Two-dose COVID-19 vaccination often results in poor humoral response rates in patients with hematologic malignancies (HMs); yet responses to COVID-19 booster vaccines and the risk of COVID-19 infection post-booster are mostly uncertain. Methods: We included 200 outpatients with HMs and predominantly lymphoid neoplasms (96%, 191/200) in our academic center and reported on the humoral responses, which were assessed by measurement of anti-spike IgG antibodies in peripheral blood as early as 14 days after mRNA-based prime-boost vaccination, as well as factors hampering booster efficacy. Previous basic (double) immunization was applied according to the local recommendations with mRNA- and/or vector-based vaccines.
View Article and Find Full Text PDFCOVID-19 vaccines have become an integral element in the protection of cancer patients against SARS-CoV-2. To date, there are no direct comparisons of the course of COVID-19 infection in cancer patients between the pre- and post-vaccine era. We analyzed SARS-CoV-2 infections and their impact on cancer in COVID-19 vaccinated and non-vaccinated patients from three German cancer centers.
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