Hypertension treatment and control prevent more cardiovascular events than management of other modifiable risk factors. Although the age-adjusted proportion of US adults with controlled blood pressure (BP) defined as <140/90 mm Hg, improved from 31.8% in 1999-2000 to 48.
View Article and Find Full Text PDFBackground: deletion/intragenic mutations are the most commonly identified genetic cause of congenital anomalies of the kidney and urinary tract (CAKUT) suggested by fetal ultrasound findings such as: parenchymal hyperechogenicity, overt cystic changes or gross morphological urinary system (UT) abnormalities. The postnatal evolution of these 17q12 deletions encompassing the gene-associated findings has not been assessed in depth.
Methods: In this observational study, we present postnatal follow-up findings in 5 of 6 cases (one pregnancy was terminated on parental request) of fetal-onset cystic/hyperechogenic kidneys eventually diagnosed with 17q12 microdeletion encompassing the gene between 2009 and 2017.
Background: This study aimed to evaluate short- and long-term outcomes of kidney transplantation over 37 years in a national referral center and compare outcomes between Israeli Jewish and Arab children.
Methods: Data on 599 pediatric transplantations performed in 545 children during 1981-2017, including demographic parameters, kidney failure disease profile, and pre-transplant dialysis duration, were retrieved from our computerized database and patient files. Patient and graft survival were estimated using the Kaplan-Meier method.
Previously, -(methanesulfonyl)azetidine () was found to polymerize anionically via ring-opening at temperatures >100 °C to form p(MsAzet) in the presence of an anionic initiator. In the current report, potassium(azetidin-1-ylsulfonyl) methanide (), formed from deprotonation of the methanesulfonyl group of by KHMDS, is shown to undergo spontaneous AROP at room temperature to form p(-K-MsAzet). The structure of p(-K-MsAzet) differs from that of p(MsAzet), as the sulfonyl groups are incorporated into the polymer backbone of p(-K-MsAzet).
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