Publications by authors named "L Reid Boyce Nichols"

Article Synopsis
  • The World Health Organization and CDC have set goals for eliminating hepatitis C virus (HCV) by 2030, but the U.S. is falling short due to various barriers such as lack of awareness, misinformation, and treatment accessibility issues.
  • The objective of the study was to create a high-quality educational app aimed at improving knowledge about HCV testing and treatment among patients and healthcare workers, featuring five interactive learning modules.
  • The app was tested with 561 users, with over a third engaging with the training modules, where many spent significant time learning about HCV, indicating an interest in improving knowledge on the disease and its treatment process.
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Background: This study provides a detailed examination of older Veterans with traumatic brain injury (TBI) and dementia and their caregivers, focusing on Veterans' demographic, clinical, functional, safety risk, and behavioral characteristics and caregivers' demographic, clinical, and care-related characteristics and well-being.

Methods: Veterans' caregivers (N = 110) completed a telephone-based survey.

Results: Veterans averaged eight comorbid health conditions, with over 60% having chronic pain, hypertension, post-traumatic stress disorder, or depression.

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Polypharmacy-related drug-drug interactions (DDIs) are a significant and growing healthcare concern. An increasing number of therapeutic drugs on the market underscores the necessity to accurately assess new drug combinations during pre-clinical evaluation for DDIs. primary human hepatocytes (PHH) models are only applicable for short term induction studies due to their rapid loss of metabolic function.

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Article Synopsis
  • * A case report details a patient who was initially misdiagnosed with a sinus headache and later with aseptic meningitis, only to be found post-mortem to have severe cryptococcal meningoencephalitis.
  • * To improve diagnosis, cerebrospinal fluid tests like nuclear acid amplification (NAA) panels should include Cryptococcus, but these can yield false positives; hence, confirming with cryptococcal antigen tests is crucial for accurate meningitis diagnosis.
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Background: The responsibility of care for Veterans and Service Members (V/SMs) with traumatic brain injury (TBI) often defaults to informal family caregivers. Caregiving demands considerable knowledge, skill, and support to facilitate the health and well-being of V/SMs and themselves. Persistent and common TBI caregiver issues include strain, depression, and anxiety.

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