Publications by authors named "L Rayburn Nigos"
Article Synopsis
- The study reveals a method to create human haemogenic DLL4+ arterial endothelial cells (AECs) from pluripotent stem cells, essential for forming blood cells during embryonic development.* -
- Using single-cell RNA sequencing, researchers tracked the development of blood cell types in human embryos, identifying key pre-haematopoietic stem cell genes along the way.* -
- The research shows that IL7 influences the decision between T cells and innate lymphoid cells and establishes a pathway for RAG1+ lymphoid precursors to develop into natural killer cells, offering insights into blood system development.*
Host cell restriction factors are intracellular proteins that can inhibit virus replication. Characterisation of novel host cell restriction factors can provide potential targets for host-directed therapies. In this study, we aimed to assess a member of the Tripartite-motif family protein (TRIM) family, TRIM16, as a putative host cell restriction factor.
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