Multi-modal, Label-free, Optical Mapping of Cellular Metabolic Function and Oxidative Stress in 3D Engineered Brain Tissue Models.

Brain metabolism is essential for the function of organisms. While established imaging methods provide valuable insights into brain metabolic function, they lack the resolution to capture important metabolic interactions and heterogeneity at the cellular level. Label-free, two-photon excited fluorescence imaging addresses this issue by enabling dynamic metabolic assessments at the single-cell level without manipulations.

Assessment of childhood intracranial pressure: a comparative study of transcranial Doppler ultrasound indices and findings at ventriculoperitoneal shunt.

Purpose: This study compares transcranial Doppler (TCD) Pulsatility Index (PI) and Resistivity Index (RI) with intra-operative CSF opening pressure measured by manometric technique during ventriculoperitoneal (V-P) shunt in children with hydrocephalus.

Methods: It was a prospective, hospital-based study performed among patients diagnosed with hydrocephalus. Patients had TCD ultrasonography before V-P shunt.

Ritual Abuse Survivors' Perspectives on Research Participation: An Exploratory Mixed Methods Online Study.

This exploratory study sought a deeper understanding of the perspectives of self-defined ritual abuse (RA) survivors, who had experienced sexual victimization, on participation in research. A mixed-methods qualitative design involving online survey and follow-up virtual interviews included 68 adults across eight countries. Content and thematic analysis of responses indicated that RA survivors were keen to be involved in a range of research activities to share their experience, knowledge, and support for other survivors.

() Is Essential for Cell Proliferation and Cell Differentiation in Tomato.

Most flowering plant species contain at least two copies of the () gene with the encoded DEM proteins lacking homology to proteins of known biochemical function. In tomato (; ), stable mutations in the locus result in shoot and root meristem defects with the mutant failing to progress past the cotyledon stage of seedling development. Generation of a () transformant line in tomato allowed for the characterization of gene function past the seedling stage of vegetative development with plants displaying a range of leaf development abnormalities.

Crosslinked Polyethylene (XLPE) Recycling via Foams.

Efficient recycling of crosslinked polyethylene has been challenging due to manufacturing difficulties caused by chemical crosslinking. This study focuses on simple processing via solid waste powder generation and particle fining for the subsequent crosslinked polyethylene inclusion and dispersion in rigid polyurethane foam. In addition, the concentration effects of crosslinked polyethylene in polyurethane were studied, showing a well-controlled foam microstructure with uniform pores, retained strength, better thermal degradation resistance, and, more importantly, increased thermal capabilities.