Publications by authors named "L Ravi Shankar"

Conventional Li-S battery cathode synthesis routes are time-consuming, energy-intensive, use toxic solvents, and yet fail to effectively confine sulfur into carbon matrices, reducing the cathode efficiency. Supercritical CO₂ (scCO2) presents notable benefits as a "green solvent" due to its affordability, chemical inertness, recyclability, non-flammability, and non-toxicity. It eliminates the need for energy-intensive post-heat treatments, providing a more sustainable and efficient option.

View Article and Find Full Text PDF

Radiographic assessment plays a crucial role in the management of patients with central nervous system (CNS) tumors, aiding in treatment planning and evaluation of therapeutic efficacy by quantifying response. Recently, an updated version of the Response Assessment in Neuro-Oncology (RANO) criteria (RANO 2.0) was developed to improve upon prior criteria and provide an updated, standardized framework for assessing treatment response in clinical trials for gliomas in adults.

View Article and Find Full Text PDF

The National Institutes of Health-US Food and Drug Administration Joint Leadership Council Next-Generation Sequencing and Radiomics Working Group was formed by the National Institutes of Health-Food and Drug Administration Joint Leadership Council to promote the development and validation of innovative next-generation sequencing tests, radiomic tools, and associated data analysis and interpretation enhanced by artificial intelligence and machine learning technologies. A 2-day workshop was held on September 29-30, 2021, to convene members of the scientific community to discuss how to overcome the "ground truth" gap that has frequently been acknowledged as 1 of the limiting factors impeding high-quality research, development, validation, and regulatory science in these fields. This report provides a summary of the resource gaps identified by the working group and attendees, highlights existing resources and the ways they can potentially be employed to accelerate growth in these fields, and presents opportunities to support next-generation sequencing and radiomic tool development and validation using technologies such as artificial intelligence and machine learning.

View Article and Find Full Text PDF