Publications by authors named "L Raul Soto"
Background: A significant proportion of individuals maintain healthy cognitive function despite having extensive Alzheimer's disease (AD) pathology, known as cognitive resilience. Understanding the molecular mechanisms that protect these individuals can identify therapeutic targets for AD dementia. This study aims to define molecular and cellular signatures of cognitive resilience, protection and resistance, by integrating genetics, bulk RNA, and single-nucleus RNA sequencing data across multiple brain regions from AD, resilient, and control individuals.
View Article and Find Full Text PDFBackground: Disseminated nocardiosis is a rare and potentially fatal disease, with a higher incidence in immunocompromised patients, such as those living with human immunodeficiency virus (HIV) or hematological malignancies, including lymphoma. Information on Nocardia spp. infection in Venezuela is limited.
View Article and Find Full Text PDFUnlabelled: The management of proteinuria in patients with lupus nephritis represents a challenge for the specialist. Recently, Calcineurin Inhibitors have been positioned as an effective alternative in these patients, but their use is not widespread in our country. We report the experience of three centers in this regard.
View Article and Find Full Text PDFArticle Synopsis
- The study examines health care disparities among minority men in California, particularly post-pandemic impacts on routine health checkup compliance.
- A survey of 266 male respondents revealed that despite high insurance coverage, only 50.8% attended routine checkups, highlighting issues related to accessibility and health insurance literacy.
- Key factors affecting compliance included demographics such as zip code and the ability to find insurance-covered clinics, indicating significant barriers that need to be addressed to improve health outcomes in this population.