Publications by authors named "L Rascle"
Introduction: To investigate the relationship between collaterals and blood-brain barrier (BBB) permeability on pre-treatment MRI in a cohort of acute ischemic stroke (AIS) patients treated with thrombectomy.
Methods: We conducted a retrospective analysis of the HIBISCUS-STROKE cohort, a single-center observational study that enrolled patients treated with thrombectomy from 2016 to 2022. Dynamic-susceptibility MRIs were post-processed to generate K2 maps with arrival-time correction, which were co-registered with apparent diffusion coefficient (ADC) maps.
Background: Left ventricular thrombus (LVT) is a source of cardiogenic embolic stroke. Conflicting data exist in the literature regarding the utilization of intravenous thrombolysis (IVT) at the acute phase of stroke in presence of LVT. We sought to assess the efficacy and safety of reperfusion therapies (IVT and/or thrombectomy) in patients with LVT.
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- The study aimed to evaluate how consistently different examiners score medical students during a neurology OSCE, focusing on the influence of examiner characteristics like specialty and gender.
- During the mock OSCE, video recordings of student performances were scored by physicians, and the reliability of scores was measured using a statistical method called intraclass correlation coefficient.
- Results showed good agreement for checklist scores but only moderate agreement for global ratings, with no impact from specialty on scoring but a correlation indicating that male examiners tended to give lower global ratings.
Article Synopsis
- The study investigates the link between left atrial enlargement (LAE), a sign of atrial myopathy, and inflammatory markers in patients who experienced acute ischemic stroke (AIS).
- Researchers analyzed inflammatory markers in the blood of 143 AIS patients treated with mechanical thrombectomy and found that a significant portion (59.4%) had LAE.
- The results showed that higher levels of VCAM-1 and sST2 were strongly associated with LAE, suggesting that these markers could indicate an ongoing inflammatory process in AIS patients with atrial issues.
Article Synopsis
- * The study aimed to investigate if inflammation linked to WMH could influence the inflammatory response in patients experiencing acute ischemic stroke (AIS).
- * Among 149 AIS patients, 38.3% had a high WMH burden, but the initial association between WMH and specific inflammatory markers did not hold true after further analysis.