Publications by authors named "L Ramos-Gomez"
Background: Several studies of spontaneous intracerebral hemorrhage (SICH) patients have shown apoptotic changes in brain samples after hematoma evacuation. However, there have been no data on the association between blood concentrations of soluble fas (sFas) (the main surface death receptor of the extrinsic apoptosis pathway) and the prognosis of spontaneous intracranial hypotension (SIH) patients.
Aim: To determine whether there is an association between blood sFas concentrations and SICH patient mortality.
Blood soluble Fas concentrations and ischemic stroke patient mortality.
Expert Rev Mol Diagn
December 2022
Background: Fas is a major receptor for cell death by apoptosis. Higher blood concentrations of soluble Fas (sFas) have been reported in patients with ischemic stroke compared to control subjects. The aim of this study was to explore the existence or not of an association between blood sFas concentrations and mortality in patients with ischemic stroke.
View Article and Find Full Text PDFConradi-Hünermann-Happle syndrome (CHHS) is a rare genodermatosis resulting from mutations in the EBP (emopamil binding protein) gene. Dermatologic manifestations may include cicatricial alopecia, ichthyosis, follicular atrophoderma, pigmentary abnormalities, and nail dystrophy. In addition to genetic testing and clinical findings, trichoscopic findings may aid in the diagnosis.
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- The "time is brain" concept highlights the critical need for quick transfer of stroke patients to medical care, and using helicopter emergency medical services (HEMS) can speed up this process and potentially improve patient outcomes.
- A systematic review of 8 studies found that while HEMS did not significantly reduce mortality rates in stroke patients, it was associated with improved overall outcomes and a lower rate of poor neurological results compared to standard emergency transport.
- The research emphasizes that while HEMS may not impact mortality significantly, it correlates with better neurological results for stroke patients, indicating its value in emergency medical response.
Fas is one of the main death receptors of the extrinsic pathway of apoptosis. A study has reported higher Fas expression in brain samples of non-surviving TBI patients than in survivors. The objective of our current study was to determine whether there is an association between Fas concentrations in blood and mortality of isolated TBI patients.
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