Publications by authors named "L Radbruch"
Background: Palliative sedation involves the intentional proportional lowering of the level of consciousness in patients with life-limiting disease who are experiencing refractory suffering. The efficacy of palliative sedation needs to be monitored to ensure patient comfort. The aim of this study was to evaluate the efficacy using discomfort levels combined with sedation/agitation levels.
View Article and Find Full Text PDFContext: Palliative care aims to improve the quality of life in patients with progressive diseases such as cancer. Effective cancer pain management is a major challenge of palliative treatment. Empirical data on the prevalence of cancer pain, the efficiency of pain treatment and influencing factors are scarce.
View Article and Find Full Text PDFArticle Synopsis
- Estimates show a significant need for palliative care in low- and middle-income countries, particularly regarding access to essential opioids for pain relief.
- The DOME (Distributed Opioids in Morphine Equivalents) methodology quantifies this need by converting procured opioid quantities into morphine equivalents, allowing for a clearer assessment of unmet pain relief requirements.
- By using DOME and its metrics, countries can evaluate their health systems' capacity for palliative care and address gaps, ultimately improving health coverage and access to necessary treatments.
Context: The WHO Model List of Essential Medicines includes 24 medications under the section Medicines for Pain and Palliative Care (EML). The Lancet Commission on Pain and Palliative Care developed the Lancet Essential Package (LEP), including 35 medications designed to alleviate serious health-related suffering worldwide.
Objectives: This study aims to provide recommendations on the appropriate use of essential of medicines in palliative care.
Background: Heart failure is a substantial global health concern that severely affects patients' quality of life. We aimed to compare the effects of early integration of palliative care (EIPC) and standard cardiac care on health status and mood of patients with non-terminal heart failure.
Methods: EPCHF was a multicentre, parallel, two-arm, open-label, randomised controlled trial carried out at University Hospital Bonn and University Hospital Düsseldorf in Germany.