Publications by authors named "L R Salgueiro"
Current therapies for Alzheimer's disease (AD) do not delay its progression, therefore, novel disease-modifying strategies are urgently needed. Recently, an increasing number of compounds from natural origin with protective properties against AD have been identified. Mixtures or extracts obtained from natural products containing several bioactive compounds have multifunctional properties and have drawn the attention because multiple AD pathways can be simultaneously modulated.
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- Type C hepatic encephalopathy (Type C HE) is a neurological disorder resulting from chronic liver failure, presenting symptoms like mental confusion and motor difficulties.
- The increase in Alzheimer type II astrocytes (AT2A) is a significant finding linked to Type C HE, though the development of AT2A and its role in cognitive impairments is still unclear.
- Research in rats indicates that elevated oxidative stress, inflammation, and specific signaling pathways contribute to the rise of GMF and AT2A, leading to cognitive and motor deficits, suggesting potential targets for treatment.
Artichokes ( L.) are valuable foods, thanks to their health benefits, but they generate significant waste during their production, harvesting, and processing, which poses sustainability issues. This study applied an agroprospecting approach to convert Tema artichoke biowaste (TB) into valuable resources, starting from a global perspective of the production chain to the targeted applications based on chemical and biological analysis.
View Article and Find Full Text PDFThe infusion of , an endemic Portuguese plant, is traditionally used to treat various infections and disorders. This study aimed to assess its chemical profile by HPLC-DAD-ESI-MS and validate its anti-inflammatory potential. In addition, the antioxidant capacity and effects on wound healing, lipogenesis, melanogenesis, and cellular senescence, all processes in which a dysregulated inflammatory response plays a pivotal role, were unveiled.
View Article and Find Full Text PDFResearch on bioactive compounds is essential to improve human health; promote adequate nutrition; drive innovation in the food, agricultural and biotechnology industries; and contribute to the preservation of the environment. The genus (Brassicaceae) currently comprises around forty species, some of which are edible, particularly (wild rocket), (wall rocket), (annual wall rocket), (perennial wall rocket), and . The leaves of these species are rich in fiber and essential minerals, such as calcium, iron, potassium, and magnesium.
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