Publications by authors named "L R O Ayres"
Minimizing the oxidation of lipids remains one of the most important challenges to extend the shelf-life of food products and reduce food waste. While most consumer products contain antioxidants, the most efficient strategy is to incorporate combinations of two or more compounds, boosting the total antioxidant capacity. Unfortunately, the reasons for observing synergistic / antagonistic / additive effects in food samples are still unclear, and it is common to observe very different responses even for similar mixtures.
View Article and Find Full Text PDFThis review provides a critical assessment of the most recent advances in digital imaging (DI) methods, applied for the development of analytical methodologies combining quantum dots (QDs). The state-of-the-art, treatment of data, instrumental considerations, software, sensing approaches, and optimization of the resulting methods are reported. Applications of the technology for the analysis of food and beverages, biomedically relevant analytes, drugs, environmental samples and forensic samples are also discussed.
View Article and Find Full Text PDFArticle Synopsis
- Despite extensive research, much of the mammalian metabolome is still unexplored, with mass spectrometry detecting many small molecules but revealing few identified metabolites.
- A novel approach using DeepMet, a chemical language model, has been developed to uncover previously unknown metabolites by learning the biosynthetic logic of known compounds.
- By combining DeepMet with tandem mass spectrometry, the research enables automated discovery of a wide range of metabolites, demonstrating the potential of language models to enhance our understanding of the metabolome.
Article Synopsis
- Physical inactivity leads to insulin resistance and metabolic issues even before significant weight gain occurs.
- Exercise performed while fasting can enhance metabolic benefits compared to exercising after eating.
- In a study with animals, exercising while fasting resulted in lower plasma cholesterol and improved fat metabolism in brown adipose tissue, showing potential advantages of fasted exercise.
Background: Low levels of knowledge among health professionals about autism spectrum disorders (ASD) can impair the care provided to people with autism. In Brazil, there are still no validated instruments that assess the knowledge of pharmacy students and pharmacists regarding ASD.
Objective: This study aimed to carry out the cross-cultural adaptation of the Autism Stigma Knowledge Questionnaire (ASK-Q) into Brazilian Portuguese and to evaluate the evidence of content validity.