Towards targeted cancer therapy: Synthesis, characterization, and biological activity of a new Cu(II)-ibuprofen-2,2'-dipyridylamine metal complex.

This work reports the synthesis of a copper metal complex with the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen, and 2,2'-dipyridylamine employing microwave-assisted synthesis (MWAS). To the best of authors knowledge, this is the first study reporting a NSAID-based complex achieved through MWAS. The coordination compound was characterised by elemental analysis, Fourier transform infrared spectroscopy, thermogravimetry, and ultraviolet-visible spectrophotometry.

Modified temporary colostomy in a dog for treatment of rectal infection after complication of perineal herniorrhaphy.

Background: Surgeries performed on the gastrointestinal system represent a significant caseload among small animal surgeries. Colostomy aims to temporarily or permanently divert the gastrointestinal tract but it is not commonly performed in veterinary medicine. Information regarding such procedures is scarce and the surgical technique is poorly described.

Association of Current and Long-Term Estradiol Use with Carotid Intima Media Thickness Among Transgender Women: A Cross-Sectional Study.

Purpose: Epidemiologic studies suggest that the transgender population has a higher burden of cardiovascular (CV) disease. We aimed to assess CV risk and investigate the relationship between estradiol (E2) or ethinylestradiol (EE) use and carotid intima media thickness (cIMT) in transgender women.

Methods: This is a cross-sectional analysis nested into a transgender-specific cohort in Rio de Janeiro, Brazil, from August 2015 to February 2018.

Cortisol, testosterone and psychosocial responses in the assessment of stress in police officers: a brief systematic review of the literature.

Given the nature of their profession, police officers cannot limit their exposure to stress and trauma, and the endocrine system plays a vital role in regulating and preparing the human body. This study aims to identify studies that have studied the behavior of the hormones cortisol and testosterone in their relationship with the physical and psychological performance of police officers and/or in a training/simulation scenario. The systematic review, limited from 2011 to 2022, was carried out according to the PICO and Preferred Reporting Items for Systematic reviews and Meta-Analyses research strategy, considering seven articles for the critical analysis (classified based on the modified Physiotherapy Evidence Database scale).