Publications by authors named "L R Michels"

Article Synopsis
  • - Intravoxel incoherent motion (IVIM) imaging is a method used in MRI that helps assess blood flow issues in the brain during acute strokes without using contrast agents.
  • - A study involving 24 stroke patients found that lower IVIM values in the infarct core and adjacent areas after treatment correlated with worse recovery outcomes 90 days later.
  • - IVIM imaging may serve as a strong predictor of long-term recovery by showing impaired blood flow in damaged brain regions, demonstrating its potential for improving stroke assessments.
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Background: The patency of intracranial stents may not be reliably assessed with either CT angiography or MR angiography due to imaging artifacts. We investigated the potential of ultra-high resolution CT angiography using a photon counting detector (PCD) CT to address this limitation by optimizing scanning and reconstruction parameters.

Methods: A phantom with different flow diverters was used to optimize PCD-CT reconstruction parameters, followed by imaging of 14 patients with intracranial stents using PCD-CT.

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Patients with visual snow syndrome (VSS) experience uncountable flickering tiny dots in the entire visual field. Symptoms often persist over the years. Very little is known about altered perception in VSS.

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Introduction: Automated CT perfusion (aCTP) is commonly used to select patients with anterior circulation large vessel occlusion (aLVO) for endovascular treatment (EVT). The equivalence of visually assessed Non-contrast CT Alberta Stroke Program Early CT Scores (ASPECTS) and aCTP based selection in predicting favorable functional outcomes remains uncertain.

Patients And Methods: Retrospective multicenter study of adult aLVO patients from the Swiss Stroke Registry (2014-2021) treated with EVT or best medical treatment 6-24 h after stroke onset.

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Article Synopsis
  • * The study involved 140 healthy older adults and 49 with mild cognitive impairment, using techniques like APOE genotyping and MRI to measure GSH levels in the brain.
  • * Findings indicated that higher GSH levels are more common in females, while older age and the presence of the APOE4 genotype are associated with increased amyloid levels, highlighting sex-specific differences in GSH levels among older adults.
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