Safety and Efficacy of Opioid-sparing Anesthesia Compared With Traditional Opioid Anesthesia: A Scoping Review.

Objectives: The rationale of adoption opioid-sparing anesthesia (OSA) is to achieve perioperative analgesia with a minimal amount of opioids combined with nonopioid adjuvants during and after surgery, namely multimodal anesthesia. The OSA approach was originally developed to overcome the known complications of opioid-based anesthesia (OA), and the present scoping review (ScR) aims at providing clinical evidence of the safety and efficacy of OSA with respect to OA.

Methods: This ScR is mainly focused on studies presenting evidence on the safety and efficacy of OSA versus OA.

Supporting those experiencing food insecurity: A scoping review of the role of a dietitian.

Background: Increasing levels of food insecurity in the United Kingdom (UK) suggest an imperative to consider the role of dietitians in supporting people who may have insufficient access to safe and nutritious food.

Objective: To explore the available evidence on the (i) role of a dietitian, (ii) impact of support and (iii) training needs of dietitians to support those with inadequate access to food.

Methods And Design: Scoping review methodology was used to identify qualitative, quantitative and grey literature on the role of dietitians in supporting those with/or at risk of food insecurity.

Metformin versus insulin in gestational diabetes mellitus: a systematic review.

Objective: The aim of this study is to assess the use of metformin with or without insulin for the treatment of Gestational Diabetes Mellitus compared to insulin alone.

Data Sources: This article consists of a systematic review of randomized clinical trials. The searches were carried out on MEDLINE including 7 studies, between 2010 to 2021.

Transcriptome-guided breeding for Paspalum notatum: producing apomictic hybrids with enhanced omega-3 content.

Transcriptomics- and FAME-GC-MS-assisted apomixis breeding generated Paspalum notatum hybrids with clonal reproduction and increased α-linolenic acid content, offering the potential to enhance livestock product's nutritional quality and reduce methane emissions A low omega-6:omega-3 fatty acid ratio is considered an indicator of the nutritional impact of milk fat on human health. In ruminants, major long-chain fatty acids, such as linoleic acid (18:2, omega-6) and α-linolenic acid (18:3, omega-3), originate from dietary sources and reach the milk via the bloodstream. Since forages are the primary source of long-chain fatty acids for such animals, they are potential targets for improving milk lipid composition.

Variation in whale (Cetacea) inner ear anatomy reveals the early evolution of "specialized" high-frequency hearing sensitivity.

As fully aquatic mammals, hearing is arguably the most important sensory component of cetaceans. Increasingly, researchers have been harnessing computed tomography (CT) to investigate the details of the inner ear as they can provide clues to the hearing abilities of whales. We use microCT scans of a broad sampling of the ear bones (periotics) of primarily toothed whales (Odontoceti) to investigate the inner ear bony labyrinth shape and reconstruct hearing sensitivities among these cetaceans, including several taxa about which little is currently known.