Publications by authors named "L R Lowe"

This work describes the design and implementation of optics for EXCLAIM, the EXperiment for Cryogenic Large-Aperture Intensity Mapping. EXCLAIM is a balloon-borne telescope that will measure integrated line emission from carbon monoxide at redshifts z < 1 and ionized carbon ([CII]) at redshifts z = 2.5 - 3.

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  • Lake Michigan's nearshore regions, influenced significantly by nearby rivers, show total phosphorus (TP) concentrations exceeding the GLWQA's target of 7 μg L, raising concerns about nutrient-related issues.
  • A monitoring program utilizing phosphorus-based models linked to hydrodynamic models was implemented to assess these nearshore conditions, revealing variability in TP concentrations due to the area's dynamic nature.
  • The study found that while model predictions varied, they successfully illustrated temporal and spatial trends, indicating that hydrodynamics and river loads critically influence TP levels, thereby making the TP model a valuable tool for future assessments.
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Background: Asthma is associated with impaired lung function; however, it is uncertain if a lower childhood lung function is associated with asthma onset and persistence during adolescence. The aims of the present study were to investigate the association between childhood lung function and onset and persistence of asthma during adolescence.

Methods: In the population-based BAMSE (Sweden), PIAMA (Netherlands) and MAAS (UK) birth cohorts, we analysed the association of forced expiratory volume in 1 s (FEV), forced vital capacity (FVC), FEV/FVC and forced expiratory volume at 75% of FVC at age 8 years with asthma onset and persistence in adolescence (age 12-16 years) using cohort-specific logistic regression analysis followed by meta-analysis.

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  • * The research shows that fatty acid vesicles can endure high osmotic pressures and retain their contents, unlike traditional phospholipid systems that tend to burst under similar stresses.
  • * The incorporation of amphiphiles from smaller vesicles helps these giant fatty acid vesicles adapt, promoting survival and membrane growth in challenging conditions.
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  • Chronic obstructive pulmonary disease (COPD) can be influenced by genetic factors and may stem from reduced lung growth during childhood, leading to lower lung function throughout life.
  • A polygenic risk score (PRS) was calculated using data from a large genome-wide association study and tested for its correlation with lung function in individuals aged 4-50 from multiple research cohorts.
  • Results indicated that higher PRS scores were associated with significantly lower lung function, measured by key indicators, starting from childhood and continuing into adulthood, regardless of smoking, sex, or asthma diagnosis.
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