Publications by authors named "L R Ginn"
Introduction: KRAS and KRAS inhibitors represent a major translational breakthrough for non-small cell lung cancer (NSCLC) and cancer in general by directly targeting its most mutated oncoprotein. However, resistance to these small molecules has highlighted the need for rational combination partners necessitating a critical understanding of signaling downstream of KRAS mutant isoforms.
Methods: We contrasted tumor development between Kras and Kras genetically engineered mouse models (GEMMs).
Objective: CHD predisposes children to neurodevelopmental delays. Frequent, prolonged hospitalisations during infancy prevent children with heart disease from participating in recommended language and cognitive development programmes, such as outpatient early childhood literacy programmes, and contribute to caregiver stress, a risk factor for adverse developmental outcomes. This study aims to describe the implementation of a single-centre inpatient early childhood literacy programme for hospitalised infants with heart disease and assess its impact on reading practices and patient-family hospital experience.
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- * A study involving interviews with 29 child and adolescent psychiatrists revealed that most believe PRS currently have limited clinical usefulness and are not ready for implementation, despite some clinician interest driven by family requests.
- * Concerns were raised by psychiatrists about the challenges of using PRS, including potential misinterpretation, misuse by third parties, and the risk of increased stigma or even eugenics-related issues, underscoring the need for careful consideration in the adoption of this technology.
Article Synopsis
- A study reviewing sunscreen-related publications found that only 5.3% of the 5,927 articles specifically addressed skin of color (SOC) despite the growing awareness of this issue since 2007.
- The majority of SOC articles focus on sunscreen knowledge and patient behaviors (29%), with only a small fraction (5%) reporting clinical trials; common conditions discussed include melasma and post-inflammatory hyperpigmentation.
- Although articles on SOC increased in 2022, the overall gap in research highlights the need for more evidence to support discussions on sunscreen use among darker skin types in clinical settings.
Objective: There are clinical differences in healthy skin requirements and skin-aging features by race and ethnicity. However, individuals of color are underrepresented in dermatology-related medical information. We sought to gather information from women of color regarding their attitudes about the importance of the prevention of skin aging, available information, and perception of representation in skin-aging prevention information.
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