Publications by authors named "L R Coney"

Article Synopsis
  • The study investigates the quality and strength of drugs sourced from cryptomarkets versus those obtained offline, focusing on substances like MDMA, cocaine, and LSD.
  • Results show that drugs from cryptomarkets had a higher likelihood of containing the expected substance and were generally stronger than those from offline sources, particularly for MDMA, cocaine, and methamphetamine.
  • However, some cryptomarket drugs like MDMA tablets and amphetamine were found to be lower in strength compared to their offline counterparts.
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Implicit biases may negatively influence healthcare providers' behaviors toward patients from historically marginalized communities, impacting providers' communication style, clinical decision-making, and delivery of quality care. Existing interventions to mitigate negative experiences of implicit biases are primarily designed to increase recognition and management of stereotypes and prejudices through provider-facing tools and resources. However, there is a gap in understanding and designing interventions from patient perspectives.

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Introduction: Drug use and trading are typically social activities; however, supply through cryptomarkets can occur without any in-person social contact. People who use drugs alone may be at higher risk of experiencing harms, for example, due to lack of others who may call for emergency assistance. Alternatively, cryptomarkets may be a source of harm reduction information and drugs with better-known content and dose, potentially reducing the risk of adverse events.

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Due to their immune suppressive pharmacology, regenerative capacity, and immune privileged status, mesenchymal stromal cells (MSCs) are an attractive cell type to treat a variety of diseases. Genetically engineered MSCs are currently in non-clinical and clinical development for a wide range of applications including the delivery of pro-drugs and therapeutic proteins or modified to enhance their regenerative potential. Unmodified MSCs have been shown to have good safety profiles in clinical development.

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Objectives: In this study, we examined the prevalence and correlates of current synthetic cannabinoid (SC) use among high school seniors in the United States.

Methods: Monitoring the Future, an annual nationally representative survey of high school seniors, began querying current (30-day) SC use in 2014. Data were examined from the 2 most recent cohorts (2014-2015; = 7805).

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