We report the preparation and characterization of three pyrimidine-based monomers, specifically: 1-(2-diallylaminoethyl)uracil, 1-(2-diallylaminoethyl)thymine and 1-(2-diallylaminoethyl)cytosine. Monomer synthesis was initiated by reaction of the pyrimidine with ethylene carbonate to form the hydroxyethyl adduct which was subsequently chlorinated to afford the chloroethyl intermediate. Reaction of the chloroethyl derivatives with diallylamine resulted in the desired monomers.
View Article and Find Full Text PDFRadiats Biol Radioecol
July 2013
The paper represents the results of research of some functional indices of blood plasma and erythrocytes in rats obtained on days 1 and 5 after exposure of the organism to low intensive electromagnetic irradiation (EMI) with 900 MHz frequency using the following two irradiation schemes: single 2 h/1 day and fractional 0.5 h/4 days. According to the data obtained, a significant increase of lipid peroxidation (LPO) intensity is registered in animal erythrocyte membranes after the influence of 900 MHz frequency EMI irrespective of the scheme applied.
View Article and Find Full Text PDFWe report herein the synthesis and characterization of 9-(2-diallylaminoethyl) adenine. We evaluated two different synthetic routes starting with adenine where the optimal route was achieved through coupling of 9-(2-chloroethyl)adenine with diallylamine. The cyclopolymerization and cyclo-copolymerization of 9-(2-diallylaminoethyl)adenine hydrochloride salt resulted in low molecular weight oligomers in low yields.
View Article and Find Full Text PDFComparison of the data of clinical-laboratory examination and study of the specific features of folliculogenesis and ovulatory disorders in patients with ovary (167) and adrenal (76) hyperandrogenia (OHA and AHA) was conducted. As a result of the research, a significant increase of LH, combined with the decreased level of FSH, is determined in the patients with polycystic ovary syndrome, vs. the control group.
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