Background: Early neurological deterioration (END) is a critical determinant influencing the short-term prognosis of acute ischemic stroke (AIS) patients and is associated with increased mortality rates among hospitalized individuals. AIS frequently coexists with coronary heart disease (CHD), complicating treatment and leading to more severe symptoms and worse outcomes. Shared risk factors between CHD and AIS, especially elevated low-density lipoprotein cholesterol (LDL-C), contribute to atherosclerosis and inflammation, which worsen brain tissue damage.
View Article and Find Full Text PDFHighly fluorinated naphthyl aldehyde and binaphthyl aldehyde ()- were designed and synthesized for fluorous-phase-based sensing. Greatly enhanced sensitivity and chemoselectivity in going from to ()- in the fluorescent detection of cysteine has been discovered. This is attributed to the increased structural rigidity of the axially chiral binaphthyl unit in ()- upon reaction with cysteine to form the corresponding thiazolidine product.
View Article and Find Full Text PDFPurpose: The human trial aimed to study the influence of propolis on immune function in the elderly.
Methods: Non-institutionalized community-dwelling individuals aged 60-80 years were recruited from Tianjin, China. Participants were assigned randomly to either the Chinese propolis group (600 mg/day, n = 32) or the control group (n = 30).