Publications by authors named "L Proppe"
Systematic review - Adjuvant radiotherapy of the vulva in primary vulvar cancer.
Gynecol Oncol
November 2024
Objective: Adjuvant radiotherapy to the vulva in vulvar squamous cell carcinoma (VSCC) is frequently performed albeit strong evidence is lacking. This systematic review aims to summarize the current literature on this topic.
Methods: 19 retrospective studies were included and analyzed, focusing on the primary outcome of local recurrence.
Introduction: NR2F6 (nuclear receptor subfamily 2 group F member 6, also called Ear-2) is known to be an orphan nuclear receptor that has been characterized as an intracellular immune checkpoint in effector T cells and, therefore, may control tumor development and growth. The prognostic impact of NR2F6 in endometrial cancers is evaluated in this study.
Materials And Methods: Expression analysis of NR2F6 in 142 endometrial cancer patients was performed by immunohistochemistry of primary paraffin‑embedded tumor samples.
Surgical treatment of endometrioid endometrial carcinoma - laparotomy versus laparoscopy.
J Turk Ger Gynecol Assoc
December 2022
Article Synopsis
- Recent studies questioned the safety of laparoscopic surgery for endometrial cancer, prompting this research to compare laparoscopic and laparotomy methods in terms of cancer outcomes and surgical effectiveness.
- A retrospective analysis of 151 patients showed that laparoscopy had significantly lower blood loss, shorter hospital stays, and fewer complications compared to laparotomy, while recurrence-free and overall survival rates were similar between the two groups.
- The conclusion suggests that although oncological outcomes were comparable, laparoscopy offered better surgical results, highlighting the need for clinical trials to further investigate its efficacy for endometrial cancer treatment.
Background: Cancers and intraepithelial lesions of different anogenital areas as well as oral cancer are associated with human papilloma virus (HPV) infections.
Methods: In this study cervical, vaginal, vulvar, anal, and oral samples were taken from 509 patients visiting our dysplasia consultation clinic. HPV genotyping was performed using the EUROArray HPV test.
Objective: Rising caesarean delivery (CD) rates throughout the world are accompanied with high rates of severe maternal complications. The aim of the present study was to analyze the outcome of trial of labor after caesarean section (TOLAC) in a Western population and identify factors associated with the success of vaginal birth after caesarean section (VBAC).
Material And Methods: A retrospective study was performed at two large obstetric departments in Germany from 2008 to 2018.