[Chloramphenicol metabolism in the tissues of newborn and adult rabbits].

The in vitro studies on the metabolism of chloramphenicol in the liver, kidney and lung of 5 days old and adult rabbit as well as in the placenta (20-23 day of gestation) have been performed. The metabolites have been identified by thin-layer chromatography technique. Nonmetabolized chloramphenicol and reduction product were estimated by spectrophotometric method.