Effectiveness of high efficiency particulate (HEPA) air condition combined with the antifungal prophylaxis on incidence, morbidity and mortality of invasive fungal infections in patients with acute myeloid leukemia: a retrospective single-center study.

Introduction: Our monocentric and retrospective study aimed to investigate the clinical effectivity of HEPA filters in combination with the antifungal drug prophylaxis in patients with AML undergoing intensive chemotherapy and allogeneic stem cell transplantation (SCT).

Methods/results: We included 177 patients between 2005 and 2015 representing a total of 372 in-hospital stays, 179 in the HEPA cohort (+HEPA) and 193 in the cohort without HEPA filters (-HEPA). No significant additional benefit of HEPA filtration on the risk reduction of IFI was observed.

[Position of the patella after knee endoprosthesis. A by radiology and computerized tomography controlled study].

The position of the Patellaimplant of 35 total knee arthroplasties (PCA) in regard to the other components, to patellar ligament and to correction of axis was analysed. The position of the patella was investigated with an average follow up of 38 months both radiologically and by computed tomography. A lateralisation of 4 mm on average and a lateral tilting of 4 degrees on average were found.