Publications by authors named "L Portengen"
Article Synopsis
- Benzene is linked to human carcinogenicity, notably causing acute myeloid leukemia, with limited evidence for lung cancer connections.
- A systematic review and meta-analysis were conducted on occupational benzene exposure and lung cancer risk, involving 13 studies with over 366,000 participants.
- Results indicated a slight elevation in lung cancer risk associated with occupational benzene exposure, with higher risks observed in well-exposed, high-quality studies that included both genders, concluding that there is a positive association between benzene exposure and lung cancer risk.
Background: Asthma and allergic diseases are among the common causes of morbidity and mortality globally. Various environmental pollutants are linked to the development of asthma and allergic diseases. Evidence on the role of oxidative stress and immune markers in the association of environmental pollutants with asthma and allergy is scant.
View Article and Find Full Text PDFCorrection to "Multiomic Signatures of Traffic-Related Air Pollution in London Reveal Potential Short-Term Perturbations in Gut Microbiome-Related Pathways".
Environ Sci Technol
October 2024
Article Synopsis
- Individual participant data (IPD) meta-analysis allows for better understanding of interaction and effect modification compared to traditional studies, especially in public health contexts.
- The text emphasizes the importance of focusing on additive interactions rather than just multiplicative ones, particularly using measures like Relative Excess Risk due to Interaction (RERI).
- A three-step method is proposed to correctly estimate additive interaction across studies, ensuring valid results when analyzing factors like the link between depression, smoking, and cancer risk using available data.
The domestic combustion of locally sourced smoky (bituminous) coal in Xuanwei and Fuyuan counties, China, is responsible for some of the highest lung cancer rates in the world. Recent research has pointed to methylated PAHs (mPAHs), particularly 5-methylchrysene (5MC), within coal combustion products as a driving factor. Here we describe measurements of mPAHs in Xuanwei and Fuyuan derived from controlled burnings (i.
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