Publications by authors named "L Pike"
Consensus Radiation Treatment Planning Guidelines Utilizing (68)Ga-DOTATATE PET/CT for Resected Meningiomas.
Int J Radiat Oncol Biol Phys
December 2024
Background: Meningiomas are the most common primary intracranial tumor. Somatostatin receptor 2 (SSTR 2) is almost universally expressed in meningioma tissue. For patients who require adjuvant radiation, SSTR based (68)Ga-DOTATATE positron emission tomography (PET) imaging can detect additional or residual disease not discernible on magnetic resonance imaging (MRI).
View Article and Find Full Text PDFColorectal cancer (CRC) is one of the most prevalent and deadly forms of cancer. It is universally treated with a combination of the DNA damaging chemotherapy drugs irinotecan, 5-Fluorouracil (5-FU), and oxaliplatin. is a novel oncogene that plays critical roles in chromatin remodeling and DNA damage repair, as well as the regulation of malignant gene expression.
View Article and Find Full Text PDFArticle Synopsis
- Lung cancer has a high chance of spreading to the brain, affecting both non-small cell and small cell types.
- Radiation therapy is crucial for treating brain metastases, with new techniques like stereotactic radiosurgery being researched for better outcomes.
- The future of treatment is leaning towards personalized approaches that combine different therapies while also considering patients' cognitive health.
Article Synopsis
- The study looked at patients with brain tumors caused by colorectal cancer to see how to better treat and watch them.
- Researchers wanted to find out what factors could help predict how long patients might live and how their tumors might grow after treatment with a specific therapy called stereotactic radiosurgery (SRS).
- The results showed that many patients with these brain tumors also have other cancer spreading in their body, and certain genetic changes in their tumors can help understand how their health might change after treatment.