Publications by authors named "L Petrica"
: Vitamin K deficiency in chronic kidney disease (CKD) could potentially occur due to multiple factors, leading to an increased risk of vascular and valvular calcifications. Vitamin K status can be indirectly assessed by measuring the blood levels of vitamin K-dependent proteins (VKDPs), such as matrix GLA protein (MGP). This study aims to examine the relationship between the levels of inactive MGP (dp-uc MGP) and the presence of valvular calcifications, as well as its association with mortality in hemodialysis patients.
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- The IHCNP study was an 18-month observational research focused on patients with mild cognitive impairment (MCI) post-ischemic stroke in Romania.
- The analysis involved 100 patients who underwent various cognitive assessments at baseline and follow-ups to track changes over time.
- Results showed significant cognitive decline by the end of the study, emphasizing the necessity for early diagnosis and continuous monitoring to better manage MCI progression in post-stroke patients.
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- Acromegaly is a rare disorder that results from excessive growth hormone from a pituitary tumor, potentially leading to kidney issues, diabetes, and hypertension.
- A case-control study compared 23 acromegalic patients to 21 healthy individuals, measuring various kidney function parameters like serum creatinine and urinary albumin/creatinine ratio.
- Results showed acromegalic patients had higher urinary albumin/creatinine ratios and lower estimated glomerular filtration rates, but no signs of kidney damage were detected through biomarkers like nephrin and KIM-1, suggesting more research is needed for early kidney involvement detection.
: Over the years, it was noticed that patients with diabetes have reached an alarming number worldwide. Diabetes presents many complications, including diabetic kidney disease (DKD), which can be considered the leading cause of end-stage renal disease. Current biomarkers such as serum creatinine and albuminuria have limitations for early detection of DKD.
View Article and Find Full Text PDFBackground: The importance of identifying mortality biomarkers in chronic kidney disease (CKD), and especially in patients treated with hemodialysis (HD), has become evident. In addition to being a marker of tubulointerstitial injury, plasma kidney injury molecule-1 (KIM-1) has been mentioned in regard to HD patients as a risk marker for cardiovascular (CV) mortality and coronary artery calcification. The aim of this study was to assess the level of plasma KIM-1 as a marker of cardiovascular disease (CVD) and mortality in CKD5-HD patients (patients with CKD stage G5D treated with hemodialysis).
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