Tamoxifen therapy for the management of pubertal gynecomastia: a systematic review.

Objective: A systematic review to assess the efficacy of tamoxifen in the management of idiopathic pubertal gynecomastia.

Data Sources: Searches were conducted using the databases of Medline (search engine PubMed) and Web of Science®.

Study Selection: Studies reporting the use of Tamoxifen for the treatment of gynecomastia in adolescents.

Functioning pulmonary metastases of thyroid cancer: does radioiodine influence the prognosis?

Functioning pulmonary metastases are the most common distant lesions of differentiated thyroid cancer. About 50% of patients with such metastases die within 10 years. The impact of iodine-131 therapy is controversial.

Parathyroid gland radionuclide scanning--methods and indications.

The usefulness of preoperative radionuclide scanning of the parathyroid glands in patients with primary or secondary hyperparathyroidism was long controversial because available techniques were of limited diagnostic efficacy. Technetium-99m-labeled sestamibi (99Tc-sestamibi) is a new radiopharmaceutical agent easily detected by gamma cameras. The first parathyroid imaging studies done with 99Tc-sestamibi about 10 years ago used a double-phase technique to separate thyroid and parathyroid tissue.