Publications by authors named "L Pennington"
Article Synopsis
- The study focused on how families of children with neurodisabilities in England experienced changes in health, education, and social care services during the COVID-19 pandemic.
- It involved qualitative interviews with 48 parent carers and 9 young people, revealing significant disruptions in communication and access to services.
- Four key themes emerged: poor communication of changes, varying access to services, detrimental impacts on families, and recommendations for future emergencies.
Aim: To seek consensus on recommendations for the delivery of services to disabled children in England during future emergencies.
Method: Candidate recommendations were drafted based on our related mapping review and qualitative research related to experiences during the COVID-19 pandemic. Iterative workshops with professionals and parent carers helped to refine the recommendations.
Article Synopsis
- The FEEDS study aimed to improve feeding methods for children with neurodisabilities and EDSD, gathering insights from healthcare professionals and parent carers to design an effective intervention toolkit.
- Survey data was collected from a variety of healthcare professionals and categorized by the child’s main diagnosis, showing that many interventions are commonly used across different conditions, but some are preferred for specific diagnoses.
- The findings indicate that interdisciplinary collaboration is vital in managing EDSD, as intervention choices are not heavily influenced by a child's diagnosis but rather by their unique circumstances.
Objectives: To understand how health, education and social care services for disabled children changed during the COVID-19 pandemic, what did or did not work well and what the impacts of service changes were on both professionals and families.
Design: Qualitative study using semistructured interviews.
Setting: Telephone and video call interviews and focus groups with professionals working in one of five local authority areas in England.
The etiology of allergy is closely linked to type 2 inflammatory responses ultimately leading to the production of allergen-specific immunoglobulin E (IgE), a key driver of many allergic conditions. At a high level, initial allergen exposure disrupts epithelial integrity, triggering local inflammation via alarmins including IL-25, IL-33, and TSLP, which activate type 2 innate lymphoid cells as well as other immune cells to secrete type 2 cytokines IL-4, IL-5 and IL-13, promoting Th2 cell development and eosinophil recruitment. Th2 cell dependent B cell activation promotes the production of allergen-specific IgE, which stably binds to basophils and mast cells.
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