Publications by authors named "L Pellegrinelli"
Article Synopsis
- A significant rise in enterovirus D68 (EV-D68) cases has been observed in northern Italy since July 2024, leading to an outbreak of acute respiratory infections that now represents about 90% of enterovirus infections in the region.
- Surveillance efforts, both community-based and hospital-based, have identified EV-D68 in patients with varying severity of respiratory symptoms, linking it to two specific strains, B3 and a unique A2 lineage.
- There has also been a noticeable increase in cases among adults, highlighting the need for improved surveillance and molecular analysis of EV-D68 throughout Europe.
A new case of Echovirus 11 neonatal fulminant hepatitis involving male twins in a Northern Italy Tertiary University Hospital: Insight on a possible immunological clue.
Federica Novazzi Antonio Piralla Simona Perniciaro Angelo Paolo Genoni Francesca Drago Ferrante Laura Pellegrinelli
IJID Reg
September 2024
The European Center for Disease Prevention and Control has reported 19 cases of severe echovirus 11 infections in neonates since 2022, nine of which were fatal. We report a new fatal neonatal case that occurred in a male twin for which we evaluated the respiratory and intestinal mucosal innate immune response.
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- * A study analyzing over 54,000 respiratory samples from January 2022 to June 2023 found adenovirus in 6.6% of acute respiratory infections, with a median patient age of 3 years, and a significant portion of cases included co-infections with other viruses, especially rhinovirus.
- * Genotyping revealed six different adenovirus genotypes circulating in Italy, with type B3 being the most prevalent.
Background: Following the pandemic restrictions, the epidemiology of respiratory syncytial virus (RSV) has changed, leading to intense hospitalization peaks.
Objectives: This study, conducted at multiple sites in Italy, aimed to describe the temporal dynamics of two post-COVID-19 RSV epidemics. Additionally, the circulating RSV-A and -B lineages were characterized and compared to those found in 2018 and 2019.