Publications by authors named "L Pejkovic"
Article Synopsis
- A study was conducted in Southern Croatia to assess how common HPV is and its types among women, while also checking for other microbes in the female reproductive system.
- 1050 asymptomatic women underwent gynecological exams and tests, revealing that 10.2% had high-risk HPV (HR-HPV) infections.
- Results showed a correlation between certain bacteria and an increased frequency of HPV infections, suggesting that STI screening could be beneficial for monitoring women at risk for cervical cancer.
Aim: The aim of this study was to evaluate the prevalence of HPV types in the female population with either normal or abnormal Pap smears in Southern Croatia (Dalmatia County) and to evaluate the distribution of HPV types and their association with different cytological findings.
Methods: During one year period, we routinely screened 1,160 women for HR HPV at the Educational Public Health Institute of Split and Dalmatia County, by using Hybrid Capture 2 HPV DNA test. Only HR HPV positive specimens determined by HC2 were further genotyped by polymerase chain reaction (PCR) based assay at the Department of Pathology and Forensic Medicine, Split.
Aim: An intrauterine device (IUD), used by millions of women worldwide, is one of the most efficient methods of contraception. The goal of our study was to compare a group of women using the IUD to a control group.
Material & Methods: The survey included 236 women of fertile age from gynaecological practices in the area of Split and Dalmatia County, Croatia.
The intrauterine device (IUD), one of the most effective and most common methods of reversible contraception, is used by millions of women worldwide. Although various studies indicate the benefits of its use as a contraceptive method, the greatest concern regarding IUDs is the potential risk for infection. The presence of the IUD gives a solid surface for bacterial attachment and biofilm formation.
View Article and Find Full Text PDFObjective: To assess the value of Ki-67 quantitative analysis in cervical intraepithelial neoplasia (CIN) in relation to CIN grading and human papillomavirus (HPV) group typing.
Methods: Cervical samples selected retrospectively from 106 cases were analyzed immunohistochemically for Ki-67-positive nuclei in 3 epithelial layers and by polymerase chain reaction for HPV typing.
Results: The proportion of high-risk HPV positivity was 0% in normal controls and 30% in CIN 1, 57% in CIN 2, and 90% in CIN 3 groups, and there was no low-risk HPV finding in CIN 2 and CIN 3 cases (P < 0.