Publications by authors named "L Pedersen"
TP53 Mutation Is the Only Robust Mutational Biomarker for Outcome Found in a Consecutive Clinical Cohort of Real-Word Patients With Primary Large B-Cell Lymphoma.
Eur J Haematol
December 2024
Introduction: Large B-cell lymphoma (LBCL) taxonomy has moved in the direction of a molecular classification, but further clinical experience is needed. We present high-risk gene mutations, which predict outcome in an exploratory study of a consecutive real-world cohort of patients with primary LBCL treated with R-CHOP or R-CHOP-like therapy.
Methods: The study was a Registry Study Research Project.
Introduction: Extramedullary disease (EMD) is a rare manifestation of Waldenström macroglobulinemia (WM), and its clinical and prognostic implications are poorly understood.
Methods: In this single-center study, we investigated the clinical significance of EMD in a cohort of 469 WM patients.
Results: EMD was identified in 30 (6.
Objectives: Since 2008, patients have had access to reimbursed analgesics, including opioids, for chronic pain in Norway. There is a need for knowledge on the occurrence and trends over time of substance use disorder (SUD) diagnoses among patients who receive reimbursed opioids for chronic pain. The primary aim of this study was to investigate the prevalence of SUD diagnoses in patients with chronic pain using reimbursed opioids from 2010 to 2019 in Norway.
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- Patients with rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) face a significantly higher risk of adverse pregnancy outcomes, including preterm births and low birth weight infants.
- A study conducted in Denmark from 2008-2018 analyzed 503,491 singleton pregnancies, with 2,206 involving mothers with RA and JIA, looking at fetal growth and risks such as being small for gestational age.
- Findings indicated that while RA and JIA did not reduce estimated fetal weight, corticosteroid and sulfasalazine use during pregnancy were linked to poorer fetal growth and higher risks of small for gestational age infants.
Introduction: Continuous monitoring of respiratory rate in hospital wards can provide early detection of clinical deterioration, thereby reducing mortality, reducing transfers to intensive care units, and reducing the hospital length of stay. Despite the advantages of continuous monitoring, manually counting every 1-12 h remains the standard of care in most hospital wards. The objective of this study was to validate continuous respiratory rate measurements from a radar-based contactless patient monitor [Vitalthings Guardian M10 (Vitalthings AS, Norway)] in a hospital ward.
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