[Research ethics committees in the Autonomous City of Buenos Aires: 14 years after the implementation of Law 3301.].

This article analyzes the implementation of research ethics committees in the Autonomous City of Buenos Aires, a process that took place in the context of a historical process of implementing health research policies at both the national and jurisdictional levels. Employing a qualitative, observational, and cross-sectional approach, we gathered secondary sources of public information and conducted semi-structured, in-depth interviews with members of the committees in the Autonomous City of Buenos Aires. The results are presented in relation to three aspects: 1) the composition of the research ethics committees; 2) work processes, emphasizing the impact of the COVID-19 pandemic; and 3) obstacles and proposals, that focuses on improvements identified by committee members.

Case report and systematic review of iatrogenic left atrial dissection in different cardiovascular specialties: A common treatment for an uncommon complication?

Objectives: Left atrial dissection (LatD) is a rare and heterogeneous condition affecting many cardiovascular areas. The present article, by the means of personal case report illustration and systemic review of different clinical management, is aimed to give to clinicians further knowledge on this controversial topic.

Background: LatD is an exceedingly rare but potentially fatal complication of cardiac surgery or catheter-based interventional procedures.

Early use of beta blockers in patients with cocaine associated chest pain.

Background: The most common symptom of cocaine abuse is chest pain. Cocaine induced chest pain (CICP) shares patho-physiological pathways with the acute coronary syndromes (ACS). A key event is the increase of activity of the adrenergic system.

New oral anticoagulants in patients with cancer: current state of evidence.

Effectiveness of new oral anticoagulants (NOAC) in patients with cancer is not clearly defined. There remain concerns of doubtful benefit and chances of potential harm with newer agents. In this meta-analysis, we evaluated the efficacy and safety of NOAC in patients with cancer.

Incidence, predictors, and evolution of conduction disorders and atrial arrhythmias after contemporary mitral valve repair.

Background: Conduction disorders (CD) and atrial arrhythmias (AA) in the postoperative period of cardiac surgery impede prompt clinical recovery and prolong hospitalization. Mitral valve repair (MVR) has become the treatment of choice for patients with significant valvular regurgitation, but information on CD and AA in this population is scarce.

Methods: Records of consecutive patients undergoing MVR at a single center were reviewed.