Bone Marrow Quality Index: A Predictor of Acute Graft-versus-Host Disease in Hematopoietic Stem Cell Transplantation for Thalassemia.

Bone marrow (BM) continues to be the preferred source of stem cells in allogenic transplantation for nonmalignant disorders. Granulocyte colony-stimulating factor (G-CSF)-primed BM is associated with low rates of acute graft-versus-host disease (aGVHD) and allows reduced collection volumes while ensuring speedy engraftment. However, variability in BM harvest quality is a concern.

Musculoskeletal Disorders in Tyre Manufacturing Workers.

Background: Tyre manufacturing workers are at risk of developing WRMSDs as their job repeatedly involves elevated arm postures, lifting of tyres, pushing or pulling trolleys, trunk bending and twisting.

Aim: To assess WRMSDs in tyre manufacturing workers.

Methodology: This was an observational study involving 99 tyre manufacturing workers.

Design and development of safe gait prosthetic knee joint in India.

Context: The prosthetic technology in recent years has grown by leap and bounds. The most advanced gadgets like microprocessors are available worldwide at exorbitant costs. Developing countries have issues with terrain, access to services, and cost.

Setting up and sustaining blood and marrow transplant services for children in middle-income economies: an experience-driven position paper on behalf of the EBMT PDWP.

Severe blood disorders and cancer are the leading cause of death and disability from noncommunicable diseases in the global pediatric population and a major financial burden. The most frequent of these conditions, namely sickle cell disease and severe thalassemia, are highly curable by blood or bone marrow transplantation (BMT) which can restore a normal health-related quality of life and be cost-effective. This position paper summarizes critical issues in extending global access to BMT based on ground experience in the start-up of several BMT units in middle-income countries (MICs) across South-East Asia and the Middle East where close to 700 allogeneic BMTs have been performed over a 10-year period.

Functional ambulation with bent knee prostheses for an adult with bilateral 90 degrees knee flexion contractures-A case report.

An adult male who never stood, ambulating on all four due to bilateral severe knee flexion contractures, since his childhood, was 21 years of age, and not deterred by his condition, was pursuing his higher education. He was coaxed by his friends to seek medical opinion and it was decided to give a trial and let the client have a feel of bipedal stance and ambulation. Although there is a paucity of recent evidence on the use of bent knee prosthesis, the trial successfully restored the dignity.