Publications by authors named "L Papetti"
RHOBTB2-related paroxysmal hemiparesis: From alternating hemiplegia to hemiplegic migraine.
Parkinsonism Relat Disord
February 2025
We report a young patient harboring a RHOBTB2 likely pathogenic variant with recurrent episodes of headache, dysautonomia and hemiplegia consistent with hemiplegic migraine. Such episodes were responsive to flunarizine prophylaxis. Ictal MRI showed contralateral hemispheric hypoperfusion.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates coping strategies in adolescents with primary migraines, focusing on their responses to stress and how these relate to migraine characteristics like frequency and intensity.
- It highlights that school and socialization are common stressors, with high-frequency headache patients using less effective coping methods, leading to increased anxiety and depression.
- The findings suggest a connection between the maladaptive coping strategies and psychological symptoms, indicating the need for tailored interventions for young migraine sufferers.
Article Synopsis
- * A total of 98 patients with migraine and 98 healthy controls were analyzed for gut microbiota diversity and metabolic pathways in fecal samples, finding significant differences between the two groups.
- * Results indicated that migraine patients had greater bacterial richness and specific metabolic changes, along with markers of gut inflammation and increased intestinal permeability, highlighting the distinct GM profiles in pediatric migraine cases.
Angulated-screw channels (ASCs) allow the clinician to employ screw-retained restorations in almost all cases, as the access hole can be moved away from the vestibular portion of the crown, where it would jeopardize the final esthetic result. The objective of this study was to compare screw-retained restorations employing ASCs with restorations cemented on angled abutments. In this study, 30 subjects, equally divided into two groups: group 1 (cemented restorations on angulated abutments) and group 2 (screw-retained restorations adopting ASCs), were treated and retrospectively compared after 2 years using the pink esthetic score (PES) and the white esthetic score (WES).
View Article and Find Full Text PDFBackground: Pediatric-onset Multiple Sclerosis (POMS) patients show more inflammatory disease compared with adult-onset MS. However, highly effective treatments are limited with only fingolimod being approved in Italy and natalizumab prescribed as off-label treatment.
Objectives: to compare the efficacy of natalizumab versus fingolimod in POMS.