Publications by authors named "L Paluszkiewicz"
Article Synopsis
- The study aimed to evaluate classic risk factors in patients with heart failure and their correlation with the activity of specific genes.
- It involved 150 patients, including those with heart failure due to coronary artery disease, with the most common risk factors being hypertension and obesity.
- Higher gene activity was linked to risk factors like obesity and smoking, indicating their roles in the progression of heart failure during myocardial ischemia, emphasizing the need for education on healthy lifestyle choices.
Introduction: Drug therapy to reduce the regurgitation fraction (RF) of high-grade aortic regurgitation (AR) by increasing heart rate (HR) is generally recommended. However, chronic HR reduction in HFREF patients can significantly improve aortic compliance and thereby potentially decrease RF. To clarify these contrasts, we examined the influence of HR, aortic compliance and stroke volume (SV) on RF in an ex vivo porcine model of severe AR.
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- Early right-sided heart failure (RHF) occurred in 22% of patients after receiving a left ventricular assist device (LVAD), but the best treatment for this condition remains unclear, leading to the exploration of levosimendan's effectiveness.
- The study evaluated 3,661 LVAD patients from the EUROMACS Registry, with 399 treated with levosimendan before surgery, showing that those patients had higher RHF scores and longer ICU stays, but no notable differences in RHF rates or mortality at 30 days and 1 year.
- The findings indicate that levosimendan did not significantly influence the risk of early RHF or death, suggesting the need for further research through multicenter trials for more
Background: The out-of-hospital cardiac arrest (OHCA) in the young may be associated with a genetic predisposition which is relevant even for genetic counseling of relatives. The identification of genetic variants depends on the availability of intact genomic DNA. DNA from autopsy may be not available due to low autopsy frequencies or not suitable for high-throughput DNA sequencing (NGS).
View Article and Find Full Text PDFBackground: Right ventricular (RV) strain has provided valuable prognostic information for patients with cardiac amyloidosis (CA). However, the extent to which RV strain and strain rate can differentiate CA is not yet clinically established. CA underdiagnosis delays treatment strategies and exacerbates patient prognosis.
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