Reducing reading time and assessing disease in capsule endoscopy videos: A deep learning approach.

Background: The wireless capsule endoscope (CE) is a valuable diagnostic tool in gastroenterology, offering a safe and minimally invasive visualization of the gastrointestinal tract. One of the few drawbacks identified by the gastroenterology community is the time-consuming task of analyzing CE videos.

Objectives: This article investigates the feasibility of a computer-aided diagnostic method to speed up CE video analysis.

Optimal timing for post-dialysis blood pressure measurement: relationship with home blood pressure monitoring.

In hemodialysis patients, blood pressure (BP) measured at the postdialysis period (POSBP) can be used to diagnose hypertension. However, the optimal time point for POSBP remains uncertain. This cross-sectional study evaluated 210 long-term dialysis patients (66.

Real-world tafamidis experience in hereditary transthyretin amyloidosis with peripheral neuropathy in Brazil.

Background:  Tafamidis is a kinetic stabilizer that binds to the transthyretin (TTR) gene, inhibiting its dissociation. It is the only disease-modifying treatment for hereditary TTR amyloidosis with peripheral neuropathy (ATTRv-PN) available in the National Therapeutic Form (Formulário Terapêutico Nacional, FTN, in Portuguese) of the Brazilian Unified Health System (Sistema Único de Saúde, SUS, in Portuguese).

Objective:  To assess if the efficacy and safety of tafamidis in the Brazilian real-world experience are comparable to the results of clinical trials.

Synthesis and characterization of heptacoordinated molybdenum(II) complexes supported with 2,6-bis(pyrazol-3-yl)pyridine (bpp) ligands.

Functional pincer ligands that engage in metal-ligand cooperativity and/or are capable of redox non-innocence have found a great deal of success in catalysis. These two properties may be found in metal complexes of the 2,6-bis(pyrazol-3-yl)pyridine (bpp) ligands. With this goal in mind, we have attempted the coordination of 2,6-bis(5-trifluoromethylpyrazol-3-yl)pyridine (LCF3) and its Bu analogue 2,6-bis(5--butylpyrazol-3-yl)pyridine (LtBu) to Mo(0) by reactions with mixed phosphine/carbonyl complexes [Mo(CO)(MeCN)(PMePh)] 1-3 (1 ≤ ≤ 3).

Implementing proximity care for people with multiple sclerosis in Italy: the bottom-up approach of the StayHome project.

Objective: In Italy, around 137,000 people live with multiple sclerosis, facing organizational complexities due to the current model's limited focus on proximity care. This project aims to define a proximity model, in accordance with recent developments in the Italian healthcare landscape, engaging over 150 healthcare stakeholders and potentially impacting approximately 14,000 patients.

Methods: An analysis was pursued to map the multiple sclerosis pathway, followed by interviews to capture the actual implementation in Italian Multiple Sclerosis Centers.