Outcomes following deep hypothermic circulatory arrest versus antegrade cerebral perfusion during aortic arch reconstruction.

Objective: The optimal method for cerebral protection during aortic arch reconstruction in neonates and infants is unknown. We compare the outcomes of deep hypothermic circulatory arrest and selective antegrade cerebral perfusion strategies in neonatal and infant cardiac surgery.

Methods: We retrospectively identified all patients aged less than 1 year who underwent aortic arch reconstruction from 2012 to 2023.

Glutaminolysis promotes the function of follicular helper T cells in lupus-prone mice.

Glutamine metabolism is essential for T cell activation and functions. The inhibition of glutaminolysis impairs Th17 cell differentiation and alters Th1 cell functions. There is evidence for an active glutaminolysis in the immune cells of lupus patients.

Patient-Reported Pregnancy Outcomes and Survival in Women with Aortic Valve and/or Aortic Root Replacement.

Our objective was to investigate patient-reported maternal and perinatal outcomes and survival among women undergoing aortic valve and/or aortic root replacement (AVR/ARR). This was a single-center observational study of U.S.

Mobile monitoring reveals the importance of non-vehicular particulate matter sources in London.

This study uses mobile monitoring to gain a better understanding of particulate matter (PM) sources in two areas of Central and Outer London, UK. We find that, unlike emissions of nitrogen oxides (NO + NO = NO), which are elevated in Central London due to the high number of diesel vehicles and congestion, fine particulate matter (PM) emissions are well-controlled. This finding provides evidence for the effectiveness of vehicle particulate filters, supporting the view that their widespread adoption has mitigated PM emissions, even in the highly dieselized area of Central London.