[Segregation analysis of some anthroposcopic characteristics. II. Age dependence and signs with three phenotypic variants].

Results of genetic analysis of three anthroposcopic traits, performed on a sample of pedigrees from a Kyrgyz population, are presented. The segregation analysis method used allows analysis of pedigrees of arbitrary structure with account of age dependence of genotype penetrances. The method involves analysis of not only binary traits, but also of traits with three phenotypic.

[Segregation analysis of certain anthroposcopic characteristics. I. Alternative signs with penetration independent of age].

Genetic analysis of a number of anthroposcopic traits was attempted using a sample of pedigrees from the Kirgiz population. We used methods of binary trait segregation analysis, which allowed us to analyze pedigrees of arbitrary structure. The genetic model applied was based on the monogenic diallelic mode of inheritance with arbitrary genotype penetrances and allowed for different phenotypic expressions of a genotype in males and females.

[Feasibility of monogenic control of blood cholesterol content for the Kirghiz population].

The samples presented by 67 pedigrees ascertained from the Kirghiz population via proband having an early myocardial infarction were analysed for ischemic heart disease. It is shown that these pathologies are not accompanied by high increase in the cholesterol level, as is usual for the European populations. Segregation analysis of the cholesterol level was performed and a possibility of monogenic control of this trait was demonstrated.