[Effect of a new sweetening agent from Stevia rebaudiana on animals].

Animals received saccharol adequate (by sweetness) to sugar, and in 10- and 50-fold increased amounts. The data of chronic 10-month experiments studied in the time course after 2, 5, 10 months have permitted a conclusion that saccharol included into the ration during long periods, does not produce a significant effect on the parameters of metabolic processes and morphological picture of the internal organs in test animals. Saccharol in 50-fold increased amounts inhibits the activity of oxidative phosphorylation in the hepatic tissue of rats.

[Effect of the total replacement of fats in the diet with a phospholipid concentrate on oxidative phosphorylation in liver mitochondria and the lipid composition of the plasma and liver in rats].

Experimental rats were given rations with 100% substitution of fats for phospholipid concentrate, during 1 and 3 months. It was found that such rations produced hypolipidemic and hypocholesterolemic effects, that were most pronounced at the end of the experiment. A control ration with sunflower oil containing high levels of unsaturated fatty acids induced accumulation of lipid peroxides in the hepatic tissue and blood plasma of the animals fed with the ration during 3 months.

[Effect of the meat of farm animals fed new nitrogen-containing food additives on the morphologic features of the internal organs in the rat].

A study was made of the internal organs of rats fed the meat of agricultural animals whose diet included non-protein nitrogen-containing compounds--urea, isobutylidene diurea and a polymer, carbamide with polyacrylamide. Morphological studies have demonstrated that inclusion into the diet of experimental rats of the meat of young bulls given isobutylidene diurea and urea leads to structural alterations in the internal organs of rats, the most pronounced alterations being detected in experiments with the use of the meat of young bulls given isobutylidene diurea. The feeding of experimental rats with the meat of animals grown with the use of the polymer did not affect the morphofunctional status of their organs.