Airway Microbiota Profiles in Children With and Without Asthma: A Comparative Study.

Background: Asthma is a common chronic respiratory disease that affects children and adults and can have a serious impact on their quality of life. Factors contributing to the development of asthma and related exacerbations are multifactorial, with microbial communities colonizing the airways possibly playing a key role.

Methods: The study included asthmatic (79) and healthy children (57) aged 5-16 years.

An Evaluation of Time Spent Completing Electronically Collected Patient-Reported Outcomes in Clinical Trials.

Objectives: Patient-reported outcomes (PROs) are important measures of efficacy in the context of clinical trials but are sometimes identified as time and resource intensive to study participants and site personnel. The objective of this research was to evaluate the amount of time that participants spend completing PROs via an electronic device in phase 2 and 3 clinical trials across several disease areas.

Methods: The electronic Clinical Outcome Assessment (eCOA) data were obtained from Johnson & Johnson clinical trials across various disease areas from 2016 to 2023.

Health professionals' experiences delivering an Interdisciplinary Nurse-coordinated SELf-MAnagement intervention for patients with inflammatory arthritis.

Purpose: The complex Interdisciplinary Nurse-coordinated SELf-MAnagement (INSELMA) intervention for patients with IA who experience substantial disease impact, was tested in a feasibility study. This study explored healthcare professionals' (HPs) experiences of delivering the intervention.

Materials And Methods: A qualitative longitudinal evaluation study was conducted based on four focus group interviews.

Pain, opioid consumption, and epidural anesthesia in patients with inflammatory bowel disease undergoing laparoscopic subtotal colectomy: an observational cohort study.

Background: Surgery is often needed to provide disease control in patients with inflammatory bowel disease. Studies document increased postoperative pain and complicated perioperative courses. This study examines postoperative pain and opioid consumption in patients with inflammatory bowel disease undergoing laparoscopic subtotal colectomy.

Participation in and use of skills development for work ability and expected retirement age: a cross-sectional study among senior workers.

Introduction: Europe's aging population calls for ways to prolong working life. Skills development initiatives could potentially improve work ability and extend working lives and may thus be key to address this challenge. However, the role of skills development in relation to work ability and retirement age is still not fully understood.