Neuroprotective Actions of Cannabinoids in the Bovine Isolated Retina: Role of Hydrogen Sulfide.

Both hydrogen sulfide and endocannabinoids can protect the neural retina from toxic insults under in vitro and in vivo conditions. The aim of the present study was two-fold: (a) to examine the neuroprotective action of cannabinoids [methanandamide and 2-arachidonyl glycerol (2-AG)] against hydrogen peroxide (HO)-induced oxidative damage in the isolated bovine retina and (b) to evaluate the role of endogenously biosynthesized hydrogen sulfide (HS) in the inhibitory actions of cannabinoids on the oxidative stress in the bovine retina. Isolated neural retinas from cows were exposed to oxidative damage using HO (100 µM) for 10 min.

A Unified Approach to Health Data Exchange: A Report From the US DHHS.

Importance: Health information technology, such as electronic health records (EHRs), has been widely adopted, yet accessing and exchanging data in the fragmented US health care system remains challenging. To unlock the potential of EHR data to improve patient health, public health, and health care, it is essential to streamline the exchange of health data. As leaders across the US Department of Health and Human Services (DHHS), we describe how DHHS has implemented fundamental building blocks to achieve this vision.

Collider-based movement detection and control of wearable soft robots for visually augmenting dance performance.

The fusion of wearable soft robotic actuators and motion-tracking sensors can enhance dance performance, amplifying its visual language and communicative potential. However, the intricate and unpredictable nature of improvisational dance poses unique challenges for existing motion-tracking methods, underscoring the need for more adaptable solutions. Conventional methods such as optical tracking face limitations due to limb occlusion.

Signaling (in)tolerance: Social evaluation and metaethical relativism and objectivism.

Prior work has established that laypeople do not consistently treat moral questions as being objectively true or as merely true relative to different perspectives. Rather, these metaethical judgments vary dramatically across moral issues and in response to different social influences. We offer a potential explanation by examining how objectivists and relativists are evaluated in different contexts.