[Water-electrolyte balance in patients with cerebral arachnoiditis].

The paper discusses the results of studying the water-electrolyte exchange in patients with cerebral arachnoiditis. Basically new evidence has been obtained for the mechanisms of interaction of the liquor-circulating and osmoregulating systems of the body. There is a more intensive excretion of sodium and H2O during load sodium and water tests and a decrease in antidiuretic effects on hyperosmotic exposures in patients than in healthy individuals.

[Effect of qualitatively varying nutrition on several parameters of aflatoxin B1 metabolism and toxicokinetics].

The influence of qualitatively different nutrition (physiological and that with lysine, methionine, threonine and vitamins A, B, C deficiencies) on certain toxicokinetic parameters of 3H-aflatoxin B1, after single and multiple (every day, during 5 days) intraperitoneal injections of this agent in a dose of 25 micrograms/animal, was studied in two series of experiments on growing male WAG rats with the initial bw 40-50 g. It has been proved that the main parameters of aflatoxin B1 toxicokinetics depend on the injection multiplicity and the nutrition character. It has been established that the qualitative differences in the nutrition character essentially influence the stages of aflatoxin B1 distribution in the body, the sorption and metabolic transformation in the liver, enterohepatic recirculation, the rate and correlation of the main elimination routes.

[Tritium labeling of RNA and protein of bacteriophage MS2].

Thermal activation of tritium gas is used for labeling of the nucleoprotein, phage MS 2. The obtained preparation of tritiated phage has a specific radioactivity of 20-50 Ci/mmole, is considerably infectious and appears suitable for a wide range of studies. The radioactivity is distributed between intraphage RNA and phage outer protein (approximately 1:3 ratio).

[Tritium labeling of tRNA by the tritium thermal activation method].

Tritium labelled E. coli total tRNA and tRNAPhe are prepared by action of thermally activated tritium atoms. The preparations, having the molar radioactivity up to 3.