Probing the interaction of mannose-binding lectin with healthy and sickle cell anemia red blood cells and its role in cellular biomechanics.

Mannose-binding lectin (MBL) is an important glycoprotein of the human innate immune system. Furthermore, individuals with sickle cell anemia (SCA) and MBL deficiency seem more susceptible to vaso-occlusive crises, suggesting an MBL role on HbSS red blood cells (RBCs). This study investigated the interaction of MBL with HbA (healthy) and HbSS RBCs using optical tweezers (OT) and atomic force microscopy (AFM).

The [18F] F-PSMA Probe: Chemical Perspectives.

This study discusses the chemical perspectives of the [18F]F-PSMA probe, a pivotal tool in prostate cancer imaging. [18F]Fluorine, a positron emitter with a half-life of 109.8 minutes, is produced in a cyclotron by bombarding [18O]-enriched targets with protons.

Production of Cellulose Nanoparticles from Cashew Apple Bagasse by Sequential Enzymatic Hydrolysis with an Ultrasonic Process and Its Application in Biofilm Packaging.

Cellulose nanostructures obtained from lignocellulosic biomass via enzymatic processes may offer advantages in terms of material properties and processing sustainability. Thus, in this study, cellulose nanoparticles with a spherical morphology were produced through the enzymatic hydrolysis of cashew apple bagasse (CAB). CAB was previously subjected to alkaline and acid-alkali pretreatment, and the pretreated solids were labeled as CAB-PTA and CAB-PT-HA, respectively.

Unraveling the Nanomechanical and Vibrational Properties of the Mayaro Virus.

Mayaro virus (MAYV) is an emerging mosquito-borne viral pathogen whose infection results in arthritogenic disease. Despite ongoing research efforts, MAYV biology is largely unknown. Physical virology can assess MAYV nanoparticle metastability, assembly/disassembly, and polymorphism, allowing us to understand virion architecture and dynamics.