interference leading to erroneous identification of a pathogenic variant in Black patients.

This study investigates the frequency of a clinically reported variant in , NM_000535.7:c.2523G>A p.

Reduced Aqueous Retinol-Binding Protein 3 Concentration Is Associated With Diabetic Macular Edema and Progression of Diabetic Retinopathy.

Objective: To evaluate the association of aqueous retinol-binding protein 3 (RBP3) with history of diabetic macular edema (DME) and diabetic retinopathy (DR) progression.

Research Design And Methods: RBP3 concentration was measured by ELISA in aqueous from patients undergoing cataract surgery at Joslin Diabetes Center. DR progression was defined as two-step or more worsening on the Early Treatment Diabetic Retinopathy Study severity scale, and DME history was determined by clinical diagnosis.

Searching for Scalar Field Dark Matter with LIGO.

We report on a direct search for scalar field dark matter using data from LIGO's third observing run. We analyze the coupling of size oscillations of the interferometer's beam splitter and arm test masses that may be caused by scalar field dark matter. Using new efficient search methods to maximize sensitivity for signatures of such oscillations, we set new upper limits for the coupling constants of scalar field dark matter as a function of its mass, which improve upon bounds from previous direct searches by up to four orders of magnitude in a frequency band from 10 to 180 Hz.

Adaptation of the socioecological model to address disparities in engagement of Black men in prostate cancer genetic testing.

Background: Black men consistently have higher rates of prostate cancer (PCA)- related mortality. Advances in PCA treatment, screening, and hereditary cancer assessment center around germline testing (GT). Of concern is the significant under-engagement of Black males in PCA GT, limiting the benefit of precision therapy and tailored cancer screening despite longstanding awareness of these disparities.