Porokeratosis of Mibelli in an HIV-positive patient.

Porokeratosis represents a group of disorders of epidermal keratinization that are characterized by one or more annular plaques surrounded by a histologically distinctive hyperkeratotic ridge-like border called the cornoid lamella. Many studies showed that organ transplantation and immunosuppression were associated in a significant number of cases. Furthermore, an association with squamous cell carcinoma and basal cell carcinoma has been noted in all variants of porokeratosis.

Coinfection of the central nervous system by cytomegalovirus and herpes simplex virus type 1 or 2 in AIDS patients: autopsy study on 82 cases by immunohistochemistry and polymerase chain reaction.

We evaluated the frequency and histopathological features of concomitant infections of the central nervous system (CNS) with cytomegalovirus (CMV) and herpes simplex viruses type 1 or 2 (HSV1/2) in a large series of patients who had died from AIDS. Eighty-two autopsy cases with a histological diagnosis of CMV necrotizing encephalitis were examined retrospectively. CMV and HSV1/2 were detected by immunohistochemistry (IHC) with poly- and monoclonal antibodies and by nested polymerase chain reaction (PCR) for HSV 1 and 2 on DNA extracted from paraffin blocks.

Rotary subluxation of the scaphoid: a spectrum of instability.

Rotary subluxation of the scaphoid is not an "all or nothing" phenomenon, but a spectrum of instability including constant displacement of the scaphoid apparent on plain non-stress radiographs (the previously defined static type), subluxation seen only on loading X-rays or other special studies ("dynamic"), and instability demonstrable on physical examination but not by radiographic studies ("predynamic"). A clinical study of 1,000 random individuals was carried out to determine the incidence of unilateral hypermobility of the scaphoid. 21% of the subjects were found to have an abnormal difference in mobility between their scaphoids.

The contribution of the dorsal and ventral roots of the tibial nerve in the propagation of the spinal somatosensory evoked potential in cats.

This study employed selective unilateral dorsal and ventral rhizotomy to examine the contribution of both the dorsal and ventral roots of the tibial nerve in the induction of the spinal somatosensory evoked potential (SSEP) in the cat. The spinal roots of origin of the tibial nerve in the cat were determined by retrograde transport of horseradish peroxidase (HRP). Spinal roots L6, L7, and S1 were found to give rise to the cat tibial nerve.